human ACTR2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human ACTR2.
shADV-200313
Ad-h-ACTR2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human ACTR2 (ARP2 actin related protein 2 homolog). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
actin-like protein 2; actin-related protein 2; ARP2
Description (eCommerce)
ARP2 actin related protein 2 homolog (ACTR2) functions as an ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization. Together with an activating nucleation-promoting factor (NPF), it mediates the formation of branched actin networks. ACTR2 seems to contact the pointed end of the daughter actin filament [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P61160].
Description (Vector)
The specific function of this gene has not yet been determined; however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion. Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
10097
Gene Name (eCommerce)
ARP2 actin related protein 2 homolog
Gene Name (Vector)
ARP2 actin related protein 2 homolog
Gene Symbol
ACTR2
HGNC ID
HGNC:169
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1020
Protein Name (eCommerce)
Actin-related protein 2
RefSeq ID
NM_001005386
RefSeq Synonyms
NM_005722, NM_001005386, BC036253, BC014546,
Research Areas
Cytoskeleton,EGFR Signaling,Immunology,Innate Immunity,PDGF Signaling,RAC1 Signaling,Signal Transduction
Research Areas (Faceted)
signal_transduction,cell_biology,immunology
Species
human
Target Sentence
ARP2 actin related protein 2 homolog (ACTR2) functions as an ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization. Together with an activating nucleation-promoting factor (NPF), it mediates the formation of branched actin networks. ACTR2 seems to contact the pointed end of the daughter actin filament [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P61160].
UniGene ID
Hs.643727
UniProt ID (eCommerce)
P61160
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.