human ACTN3 shRNA silencing Adenovirus

Name
Ad-h-ACTN3-shRNA

Cat No
shADV-200303

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human ACTN3.

shADV-200303

Ad-h-ACTN3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human ACTN3 (actinin alpha 3 (gene/pseudogene)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Description (Vector)

ACTN3 encodes a member of the alpha-actin binding protein gene family. The encoded protein is primarily expressed in skeletal muscle and functions as a structural component of sarcomeric Z line. This protein is involved in crosslinking actin containing thin filaments. An allelic polymorphism in this gene results in both coding and non-coding variants. The reference genome contains the non-coding allele. The non-functional allele of this gene is associated with elite athlete status.

Gene ID

Gene Name (Vector)

actinin alpha 3 (gene/pseudogene)

Gene Symbol

ACTN3

HGNC ID

HGNC:165

ORF Size (aa)

2706

ORF Size (bp)

2706 bp

RefSeq ID

NM_001104

RefSeq Synonyms

NM_001258371, NM_001104, BC099649, BC099647,

Species

human

UniGene ID

Hs.654432

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.