human ACTN2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human ACTN2.
shADV-200301
Ad-h-ACTN2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human ACTN2 (actinin alpha 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CMD1AA; CMH23
Description (Vector)
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles.
Gene ID
88
Gene Name (Vector)
actinin alpha 2
Gene Symbol
ACTN2
HGNC ID
HGNC:164
ORF Size (aa)
2685
ORF Size (bp)
2685 bp
RefSeq ID
NM_001103
RefSeq Synonyms
NM_001278344, NM_001278343, NM_001103, BC051770, BC047901,
Species
human
UniGene ID
Hs.498178
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.