human ACTB shRNA silencing Adenovirus

Name 
Ad-h-ACTB-shRNA
Cat No 
shADV-200270
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human ACTB.

shADV-200270
Ad-h-ACTB-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human ACTB (actin beta). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
actin, cytoplasmic 1; beta cytoskeletal actin; Beta-actin; BRWS1; I(2)-actin; PS1TP5-binding protein 1; PS1TP5BP1
Description (eCommerce)
Cytoskeletal beta-actin is one of six highly-conserved actin isoforms that is expressed ubiquitously in eukaryotic cells. Cytoskeletal beta-actin functions to maintain cell structure and plays a role in motility.
Description (Vector)
ACTB encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, and integrity. This actin is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins.
Gene ID
60
Gene Name (eCommerce)
actin beta
Gene Name (Vector)
actin beta
Gene Symbol
ACTB
HGNC ID
HGNC:132
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1128
ORF Size (bp)
1128 bp
Protein Name (eCommerce)
Actin, cytoplasmic 1
RefSeq ID
NM_001101
RefSeq Synonyms
NM_001101, BC016045, BC014861, BC013380, BC004251, BC002409, BC001301,
Research Areas
Axon Guidance,Cancer,Cardiology,Cardiomyopathy,Cardiovascular,Chromatin Remodeling,Cytoskeleton,EGFR Signaling,Hippo Signaling,Histone Modification,Host-Virus Interactions,Immunology,Innate Immunity,Metabolism/Metabolic Process,Neurobiology,Protein Folding,Signal Transduction,Translational Control
Research Areas (Faceted)
cancer,cardiovascular,cell_biology,genetics,immunology,infectious_disease,metabolism,neurobiology,signal_transduction,transcription_translation
Species
human
Target Sentence
Cytoskeletal beta-actin is one of six highly-conserved actin isoforms that is expressed ubiquitously in eukaryotic cells. Cytoskeletal beta-actin functions to maintain cell structure and plays a role in motility.
UniGene ID
Hs.520640
UniProt ID (eCommerce)
P60709

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.