human ACAN shRNA silencing Adenovirus

Name 
Ad-h-ACAN-shRNA
Cat No 
shADV-200162
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human ACAN.

shADV-200162
Ad-h-ACAN-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human ACAN (aggrecan). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
AGC1; AGCAN; CSPG1; CSPGCP; MSK16; SEDK
Description (Vector)
ACAN is a member of the aggrecan/versican proteoglycan family. The encoded protein is an integral part of the extracellular matrix in cartilagenous tissue and it withstands compression in cartilage. Mutations in this gene may be involved in skeletal dysplasia and spinal degeneration. Multiple alternatively spliced transcript variants that encode different protein isoforms have been observed in this gene.
Gene ID
176
Gene Name (Vector)
aggrecan
Gene Symbol
ACAN
HGNC ID
HGNC:319
ORF Size (aa)
7422
ORF Size (bp)
7422 bp
RefSeq ID
NM_001135
RefSeq Synonyms
NM_013227, NM_001135, BC150624,
Species
human
UniGene ID
Hs.711491

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.