human ABCC12 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human ABCC12.
shADV-200076
Ad-h-ABCC12-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human ABCC12 (ATP binding cassette subfamily C member 12). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
MRP9
Description (Vector)
ABCC12 is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. ABCC12 is a member of the MRP subfamily which is involved in multi-drug resistance. ABCC12 and another subfamily member are arranged head-to-tail on chromosome 16q12.1. Increased expression of this gene is associated with breast cancer.
Gene ID
94160
Gene Name (Vector)
ATP binding cassette subfamily C member 12
Gene Symbol
ABCC12
HGNC ID
HGNC:14640
ORF Size (aa)
4080
ORF Size (bp)
4080 bp
RefSeq ID
NM_033226
RefSeq Synonyms
NM_033226, BC148749, BC146310,
Species
human
UniGene ID
Hs.410111
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.