human ABCB7 shRNA silencing Adenovirus

Name
Ad-h-ABCB7-shRNA

Cat No
shADV-200062

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human ABCB7.

shADV-200062

Ad-h-ABCB7-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human ABCB7 (ATP binding cassette subfamily B member 7). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

ABC7; ASAT; Atm1p; EST140535

Description (Vector)

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been implicated in X-linked sideroblastic anemia with ataxia.

Gene ID

Gene Name (Vector)

ATP binding cassette subfamily B member 7

Gene Symbol

ABCB7

HGNC ID

HGNC:48

ORF Size (aa)

2262

ORF Size (bp)

2262 bp

RefSeq ID

NM_004299

RefSeq Synonyms

NM_004299, NM_001271699, NM_001271698, NM_001271697, NM_001271696, BC006323,

Species

human

UniGene ID

Hs.370480

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.