human AASS shRNA silencing Adenovirus

Name 
Ad-h-AASS-shRNA
Cat No 
shADV-200037
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human AASS.

shADV-200037
Ad-h-AASS-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human AASS (aminoadipate-semialdehyde synthase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
LKR/SDH; LKRSDH; LORSDH
Description (Vector)
AASS encodes a bifunctional enzyme that catalyzes the first two steps in the mammalian lysine degradation pathway. The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha-aminoadipic semialdehyde. Mutations in this gene are associated with familial hyperlysinemia.
Gene ID
10157
Gene Name (Vector)
aminoadipate-semialdehyde synthase
Gene Symbol
AASS
HGNC ID
HGNC:17366
ORF Size (aa)
2778
ORF Size (bp)
2778 bp
RefSeq ID
NM_005763
RefSeq Synonyms
NM_005763, BC172503, BC156456,
Species
human
UniGene ID
Hs.156738

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.