rat PACRG shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Rat Pacrg.
shAAV-295129
AAV-r-PACRG-shRNA
Ready-to-use AAV expressing shRNA for silencing of Rat Pacrg (Park2 co-regulated). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
RGD1561027
Description (Vector)
Suppresses cell death induced by accumulation of unfolded Pael receptor (Pael-R, a substrate of Parkin). Facilitates the formation of inclusions consisting of Pael-R, molecular chaperones, protein degradation molecules and itself when proteasome is inhibited. May play an important role in the formation of Lewy bodies and protection of dopaminergic neurons against Parkinson disease.
Gene ID
499021
Gene Name (Vector)
Park2 co-regulated
Gene Symbol
Pacrg
ORF Size (aa)
909
RefSeq ID
NM_001077677
RefSeq Synonyms
NM_001077677, BC127534,
Species
rat
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.