rat LOC687575 shRNA silencing AAV

Name
AAV-r-LOC687575-shRNA

Cat No
shAAV-294921

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Rat U2af1.

shAAV-294921

AAV-r-LOC687575-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat U2af1 (U2 small nuclear RNA auxiliary factor 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Recruits U2 snRNP to the branch point. Directly mediates interactions between U2AF2 and proteins bound to the enhancers and thus may function as a bridge between U2AF2 and the enhancer complex to recruit it to the adjacent intron.

Gene ID

687575

Gene Name (Vector)

U2 small nuclear RNA auxiliary factor 1

Gene Symbol

U2af1

ORF Size (aa)

720

RefSeq ID

NM_001044291

RefSeq Synonyms

NM_001044291, BC105905,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.