rat XYLT2 shRNA silencing AAV

Name
AAV-r-XYLT2-shRNA

Cat No
shAAV-294864

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Rat Xylt2.

shAAV-294864

AAV-r-XYLT2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Xylt2 (xylosyltransferase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

xylt-II

Description (Vector)

Probably catalyzes the first step in biosynthesis of glycosaminoglycan. Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein. Initial enzyme in the biosynthesis of chondroitin sulfate and dermatan sulfate proteoglycans in fibroblasts and chondrocytes (By similarity). Its enzyme activity has not been demonstrated.

Gene ID

64134

Gene Name (Vector)

xylosyltransferase 2

Gene Symbol

Xylt2

ORF Size (aa)

2595

ORF Size (bp)

2595 bp

RefSeq ID

NM_022296

RefSeq Synonyms

NM_022296, BC105767,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.