rat JTV1 shRNA silencing AAV

Name 
AAV-r-JTV1-shRNA
Cat No 
shAAV-294827
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Rat Aimp2.

shAAV-294827
AAV-r-JTV1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Aimp2 (aminoacyl tRNA synthetase complex-interacting multifunctional protein 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Jtv1
Description (Vector)
Required for assembly and stability of the aminoacyl-tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor.
Gene ID
288480
Gene Name (Vector)
aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
Gene Symbol
Aimp2
ORF Size (aa)
963
RefSeq ID
NM_001037348
RefSeq Synonyms
NM_001037348, BC107947,
Species
rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.