rat HNRNPC shRNA silencing AAV

Name
AAV-r-HNRNPC-shRNA

Cat No
shAAV-294614

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Rat Hnrnpc.

shAAV-294614

AAV-r-HNRNPC-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Hnrnpc (heterogeneous nuclear ribonucleoprotein C). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

hnRNP C; Hnrpc

Description (Vector)

Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles. Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides. May play a role in the early steps of spliceosome assembly and pre-mRNA splicing. Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules.

Gene ID

290046

Gene Name (Vector)

heterogeneous nuclear ribonucleoprotein C

Gene Symbol

Hnrnpc

ORF Size (aa)

897

ORF Size (bp)

897 bp

RefSeq ID

NM_001277600

RefSeq Synonyms

NM_001277602, NM_001277601, NM_001277600, BC097346,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.