rat L3MBTL2 shRNA silencing AAV

Name
AAV-r-L3MBTL2-shRNA

Cat No
shAAV-294559

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Rat L3mbtl2.

shAAV-294559

AAV-r-L3MBTL2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat L3mbtl2 (L3MBTL2 polycomb repressive complex 1 subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27'.

Gene ID

300320

Gene Name (Vector)

L3MBTL2 polycomb repressive complex 1 subunit

Gene Symbol

L3mbtl2

ORF Size (aa)

2112

ORF Size (bp)

2112 bp

RefSeq ID

NM_001033695

RefSeq Synonyms

NM_001033695, BC101865,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.