rat PICALM shRNA silencing AAV

Name
AAV-r-PICALM-shRNA

Cat No
shAAV-294526

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Rat Picalm.

shAAV-294526

AAV-r-PICALM-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Picalm (phosphatidylinositol binding clathrin assembly protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Calm

Description (Vector)

Assembly protein recruiting clathrin and adaptor protein complex 2 (AP2) to cell membranes at sites of coated-pit formation and clathrin-vesicle assembly. May be required to determine the amount of membrane to be recycled, possibly by regulating the size of the clathrin cage. Involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscular junction.

Gene ID

89816

Gene Name (Vector)

phosphatidylinositol binding clathrin assembly protein

Gene Symbol

Picalm

ORF Size (aa)

1944

ORF Size (bp)

1944 bp

RefSeq ID

NM_053554

RefSeq Synonyms

NM_053554, BC100142,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.