rat IFI30 shRNA silencing AAV

Name
AAV-r-IFI30-shRNA

Cat No
shAAV-294434

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Rat Ifi30.

shAAV-294434

AAV-r-IFI30-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Ifi30 (IFI30, lysosomal thiol reductase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

Lysosomal thiol reductase that can reduce protein disulfide bonds. May facilitate the complete unfolding of proteins destined for lysosomal degradation. Plays an important role in antigen processing. Facilitates the generation of MHC class II-restricted epitodes from disulfide bond-containing antigen by the endocytic reduction of disulfide bonds (By similarity). Facilitates also MHC class I-restricted recognition of exogenous antigens containing disulfide bonds by CD8+ T-cells or crosspresentation (By similarity).

Gene ID

290644

Gene Name (Vector)

IFI30, lysosomal thiol reductase

Gene Symbol

Ifi30

ORF Size (aa)

747

RefSeq ID

NM_001030026

RefSeq Synonyms

NM_001030026, BC099774,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.