rat MX1 shRNA silencing AAV

Name
AAV-r-MX1-shRNA

Cat No
shAAV-294423

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Rat Mx1.

shAAV-294423

AAV-r-MX1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Mx1 (myxovirus (influenza virus) resistance 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

IFI78

Description (Vector)

Dynamin-like GTPase acting as a cell-autonomous host restriction factor against many viral pathogens. Shows activity against influenza viruses, rhabdovirus VSV, bunyavirus LACV, Thogoto virus, measles virus, Hantaan virus, Coxsackie virus CVB, Rift Valley fever virus RVFV, hepatitis B virus HBV, and Crimean-Congo hemorrhagic fever virus CCHFV|Function: May regulate the calcium channel activity of TRPCs. Ring-like assemblies may induce membrane tubulation.

Gene ID

24575

Gene Name (Vector)

myxovirus (influenza virus) resistance 1

Gene Symbol

Mx1

ORF Size (aa)

1959

ORF Size (bp)

1959 bp

RefSeq ID

NM_001271058

RefSeq Synonyms

NM_173096, NM_001271062, NM_001271061, NM_001271060, NM_001271059, NM_001271058, BC099784,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.