rat APLF shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Rat Aplf.
shAAV-294345
AAV-r-APLF-shRNA
Ready-to-use AAV expressing shRNA for silencing of Rat Aplf (aprataxin and PNKP like factor). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
RGD1565557
Description (Vector)
Nuclease involved in single-strand and double-strand DNA break repair. Recruited to sites of DNA damage through interaction with poly(ADP-ribose), a polymeric post-translational modification synthesized transiently at sites of chromosomal damage to accelerate DNA strand break repair reactions. Displays apurinic-apyrimidinic (AP) endonuclease and 3'-5' exonuclease activities in vitro. Also able to introduce nicks at hydroxyuracil and other types of pyrimidine base damage.
Gene ID
500247
Gene Name (Vector)
aprataxin and PNKP like factor
Gene Symbol
Aplf
ORF Size (aa)
213
RefSeq ID
NM_001173382
RefSeq Synonyms
NM_001173382, BC099186,
Species
rat
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.