rat NPLOC4 shRNA silencing AAV

Name
AAV-r-NPLOC4-shRNA

Cat No
shAAV-294180

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Rat Nploc4.

shAAV-294180

AAV-r-NPLOC4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Nploc4 (NPL4 homolog, ubiquitin recognition factor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Npl4

Description (Vector)

The ternary complex containing UFD1L, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1L-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope (By similarity).

Gene ID

140639

Gene Name (Vector)

NPL4 homolog, ubiquitin recognition factor

Gene Symbol

Nploc4

ORF Size (aa)

1827

ORF Size (bp)

1827 bp

RefSeq ID

NM_080577

RefSeq Synonyms

NM_080577, BC101887,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.