rat CPSF5 shRNA silencing AAV

Name
AAV-r-CPSF5-shRNA

Cat No
shAAV-294151

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Rat Nudt21.

shAAV-294151

AAV-r-CPSF5-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Nudt21 (nudix hydrolase 21). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Cpsf5

Description (Vector)

Component of the cleavage factor Im (CFIm) complex that plays a key role in pre-mRNA 3'-processing. Involved in association with CPSF6 or CPSF7 in pre-MRNA 3'-end poly(A) site cleavage and poly(A) addition. NUDT21/CPSF5 binds to cleavage and polyadenylation RNA substrates. The homodimer mediates simultaneous sequence-specific recognition of two 5'-UGUA-3' elements within the pre-mRNA. Binds to, but does not hydrolyze mono- and di-adenosine nucleotides. May have a role in mRNA export.

Gene ID

291877

Gene Name (Vector)

nudix hydrolase 21

Gene Symbol

Nudt21

ORF Size (aa)

684

ORF Size (bp)

684 bp

RefSeq ID

NM_001039004

RefSeq Synonyms

NM_001039004, BC098748,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.