rat A2LD1 shRNA silencing AAV

Name
AAV-r-A2LD1-shRNA

Cat No
shAAV-294135

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Rat Ggact.

shAAV-294135

AAV-r-A2LD1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Ggact (gamma-glutamylamine cyclotransferase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

A2ld1

Description (Vector)

Contributes to degradation of proteins cross-linked by transglutaminases. Degrades the cross-link between a lysine and a glutamic acid residue from two proteins that have been cross-linked by transglutaminases. Catalyzes the formation of 5-oxoproline from L-gamma-glutamyl-L-epsilon-lysine. Inactive with L-gamma-glutamyl-alpha-amino acid substrates such as L-gamma-glutamyl-L-alpha-cysteine and L-gamma-glutamyl-L-alpha-alanine.

Gene ID

290500

Gene Name (Vector)

gamma-glutamylamine cyclotransferase

Gene Symbol

Ggact

ORF Size (aa)

450

ORF Size (bp)

450 bp

RefSeq ID

NM_001310058

RefSeq Synonyms

NM_001310058, NM_001025634, BC098699,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.