rat SKAP1 shRNA silencing AAV

Name
AAV-r-SKAP1-shRNA

Cat No
shAAV-293997

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Rat Skap1.

shAAV-293997

AAV-r-SKAP1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Skap1 (src kinase associated phosphoprotein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Scap1; Skap55

Description (Vector)

Positively regulates T-cell receptor signaling by enhancing the MAP kinase pathway. Required for optimal conjugation between T-cells and antigen-presenting cells by promoting the clustering of integrin ITGAL on the surface of T-cells. May be involved in high affinity immunoglobulin epsilon receptor signaling in mast cells.

Gene ID

286975

Gene Name (Vector)

src kinase associated phosphoprotein 1

Gene Symbol

Skap1

ORF Size (aa)

1065

ORF Size (bp)

1065 bp

RefSeq ID

NM_173311

RefSeq Synonyms

NM_173311, BC097931,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.