rat H2AFZ shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Rat H2afz.
shAAV-293841
AAV-r-H2AFZ-shRNA
Ready-to-use AAV expressing shRNA for silencing of Rat H2afz (H2A histone family, member Z). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
H2A.Z-1
Description (Vector)
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for chromosome segregation during cell division.
Gene ID
58940
Gene Name (Vector)
H2A histone family, member Z
Gene Symbol
H2afz
ORF Size (aa)
387
RefSeq ID
NM_022674
RefSeq Synonyms
NM_022674, BC086348,
Species
rat
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.