rat KLF4 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Rat Klf4.
shAAV-293781
AAV-r-KLF4-shRNA
Ready-to-use AAV expressing shRNA for silencing of Rat Klf4 (Kruppel like factor 4). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
GKLF
Description (Vector)
Transcription factor; can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription.
Gene ID
114505
Gene Name (Vector)
Kruppel like factor 4
Gene Symbol
Klf4
ORF Size (aa)
1449
ORF Size (bp)
1449 bp
RefSeq ID
NM_053713
RefSeq Synonyms
NM_053713, BC085720,
Species
rat
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.