rat PPP1R3C shRNA silencing AAV

Name
AAV-r-PPP1R3C-shRNA

Cat No
shAAV-293679

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Rat Ppp1r3c.

shAAV-293679

AAV-r-PPP1R3C-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Ppp1r3c (protein phosphatase 1, regulatory subunit 3C). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

PTG; R5

Description (Vector)

Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown. Dramatically increases basal and insulin-stimulated glycogen synthesis upon overexpression in a variety of cell types.

Gene ID

309513

Gene Name (Vector)

protein phosphatase 1, regulatory subunit 3C

Gene Symbol

Ppp1r3c

ORF Size (aa)

954

ORF Size (bp)

954 bp

RefSeq ID

NM_001012072

RefSeq Synonyms

NM_001012072, BC085894,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.