rat APOA5 shRNA silencing AAV

Name
AAV-r-APOA5-shRNA

Cat No
shAAV-293526

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Rat Apoa5.

shAAV-293526

AAV-r-APOA5-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Apoa5 (apolipoprotein A5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

apo-AV; apoA-V

Description (Vector)

Minor apolipoprotein mainly associated with HDL and to a lesser extent with VLDL. May also be associated with chylomicrons. Important determinant of plasma triglyceride (TG) levels by both being a potent stimulator of apo-CII lipoprotein lipase (LPL) TG hydrolysis and a inhibitor of the hepatic VLDL-TG production rate (without affecting the VLDL-apoB production rate) (By similarity). Activates poorly lecithin:cholesterol acyltransferase (LCAT) and does not enhance efflux of cholesterol from macrophages.

Gene ID

140638

Gene Name (Vector)

apolipoprotein A5

Gene Symbol

Apoa5

ORF Size (aa)

1104

ORF Size (bp)

1104 bp

RefSeq ID

NM_001277264

RefSeq Synonyms

NM_080576, NM_001277264, BC089780,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.