rat CXCR3 shRNA silencing AAV

Name
AAV-r-CXCR3-shRNA

Cat No
shAAV-293288

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Rat Cxcr3.

shAAV-293288

AAV-r-CXCR3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Cxcr3 (C-X-C motif chemokine receptor 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Gpr9

Description (Vector)

Receptor for CXCL9, CXCL10 and CXCL11 and mediates the proliferation of human mesangial cells (HMC)|Function: Isoform 2 is a receptor for CXCL4 and also mediates the inhibitory activities of CXCL9, CXCL10 and CXCL11 on the growth of human microvascular endothelial cells (HMVEC). Interaction with CXCL4 or CXCL10 leads to activation of the p38MAPK pathway and contributes to inhibition of angiogenesis. Overexpression in renal cancer cells down-regulates expression of the anti-apoptotic protein HMOX1 and promotes apoptosis|Function: Isoform 3 mediates the activity of CXCL11.

Gene ID

84475

Gene Name (Vector)

C-X-C motif chemokine receptor 3

Gene Symbol

Cxcr3

ORF Size (aa)

1104

ORF Size (bp)

1104 bp

RefSeq ID

NM_053415

RefSeq Synonyms

NM_053415, BC091136,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.