rat LGALS3 shRNA silencing AAV

Name
AAV-r-LGALS3-shRNA

Cat No
shAAV-293218

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Rat Lgals3.

shAAV-293218

AAV-r-LGALS3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Lgals3 (galectin 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

AGE-R3; CBP30; gal-3; L-34

Description (Vector)

Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.

Gene ID

83781

Gene Name (Vector)

galectin 3

Gene Symbol

Lgals3

ORF Size (aa)

789

ORF Size (bp)

789 bp

RefSeq ID

NM_031832

RefSeq Synonyms

NM_031832, BC089054,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.