rat ITGA7 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Rat Itga7.
shAAV-293114
AAV-r-ITGA7-shRNA
Ready-to-use AAV expressing shRNA for silencing of Rat Itga7 (integrin subunit alpha 7). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
Integrin alpha-7/beta-1 is the primary laminin receptor on skeletal myoblasts and adult myofibers. During myogenic differentiation, it may induce changes in the shape and mobility of myoblasts, and facilitate their localization at laminin-rich sites of secondary fiber formation. It is involved in the maintenance of the myofibers cytoarchitecture as well as for their anchorage, viability and functional integrity. Isoform Alpha-7X2B and isoform Alpha-7X1B promote myoblast migration on laminin 1 and laminin 2/4, but isoform Alpha-7X1B is less active on laminin 1 (In vitro). Acts as Schwann cell receptor for laminin-2. Acts as a receptor of COMP and mediates its effect on vascular smooth muscle cells (VSMCs) maturation (By similarity). Required to promote contractile phenotype acquisition in differentiated airway smooth muscle (ASM) cells.
Gene ID
81008
Gene Name (Vector)
integrin subunit alpha 7
Gene Symbol
Itga7
ORF Size (aa)
3408
ORF Size (bp)
3408 bp
RefSeq ID
NM_030842
RefSeq Synonyms
NM_030842, BC088846,
Species
rat
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.