rat C1QA shRNA silencing AAV

Name
AAV-r-C1QA-shRNA

Cat No
shAAV-292419

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Rat C1qa.

shAAV-292419

AAV-r-C1QA-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat C1qa (complement C1q A chain). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.

Gene ID

298566

Gene Name (Vector)

complement C1q A chain

Gene Symbol

C1qa

ORF Size (aa)

738

ORF Size (bp)

738 bp

RefSeq ID

NM_001008515

RefSeq Synonyms

NM_001008515, BC086605,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.