rat TFB2M shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Rat Tfb2m.
shAAV-292347
AAV-r-TFB2M-shRNA
Ready-to-use AAV expressing shRNA for silencing of Rat Tfb2m (transcription factor B2, mitochondrial). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, it activates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity.
Gene ID
289307
Gene Name (Vector)
transcription factor B2, mitochondrial
Gene Symbol
Tfb2m
ORF Size (aa)
1194
ORF Size (bp)
1194 bp
RefSeq ID
NM_001008293
RefSeq Synonyms
NM_001008293, BC085870,
Species
rat
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.