rat NEDD9 shRNA silencing AAV

Name
AAV-r-NEDD9-shRNA

Cat No
shAAV-292195

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Rat Nedd9.

shAAV-292195

AAV-r-NEDD9-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Nedd9 (neural precursor cell expressed, developmentally down-regulated 9). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

Docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion. May function in transmitting growth control signals between focal adhesions at the cell periphery and the mitotic spindle in response to adhesion or growth factor signals initiating cell proliferation. May play an important role in integrin beta-1 or B cell antigen receptor (BCR) mediated signaling in B- and T-cells. Integrin beta-1 stimulation leads to recruitment of various proteins including CRK, NCK and SHPTP2 to the tyrosine phosphorylated form.

Gene ID

291044

Gene Name (Vector)

neural precursor cell expressed, developmentally down-regulated 9

Gene Symbol

Nedd9

ORF Size (aa)

2502

ORF Size (bp)

2502 bp

RefSeq ID

NM_001011922

RefSeq Synonyms

NM_001011922, BC085812,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.