rat DECR2 shRNA silencing AAV

Name
AAV-r-DECR2-shRNA

Cat No
shAAV-292128

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Rat Decr2.

shAAV-292128

AAV-r-DECR2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Decr2 (2,4-dienoyl CoA reductase 2, peroxisomal). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Dcrakl; putativeperoxisomal24-dienoyl-CoAreductase

Description (Vector)

Auxiliary enzyme of beta-oxidation. Participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. Has activity towards short and medium chain 2,4-dienoyl-CoAs, but also towards 2,4,7,10,13,16,19-docosaheptaenoyl-CoA, suggesting that it does not constitute a rate limiting step in the peroxisomal degradation of docosahexaenoic acid.

Gene ID

64461

Gene Name (Vector)

2,4-dienoyl CoA reductase 2, peroxisomal

Gene Symbol

Decr2

ORF Size (aa)

879

ORF Size (bp)

879 bp

RefSeq ID

NM_171996

RefSeq Synonyms

NM_171996, BC070959,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.