rat MEF2A shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Rat Mef2a.
shAAV-292073
AAV-r-MEF2A-shRNA
Ready-to-use AAV expressing shRNA for silencing of Rat Mef2a (myocyte enhancer factor 2a). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific genes. Also involved in the activation of numerous growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. In cerebellar granule neurons, phosphorylated and sumoylated MEF2A represses transcription of NUR77 promoting synaptic differentiation.
Gene ID
309957
Gene Name (Vector)
myocyte enhancer factor 2a
Gene Symbol
Mef2a
ORF Size (aa)
1488
ORF Size (bp)
1488 bp
RefSeq ID
NM_001014035
RefSeq Synonyms
NM_001014035, BC081907,
Species
rat
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.