rat DYNC1I2 shRNA silencing AAV

Name
AAV-r-DYNC1I2-shRNA

Cat No
shAAV-291957

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Rat Dync1i2.

shAAV-291957

AAV-r-DYNC1I2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Dync1i2 (dynein cytoplasmic 1 intermediate chain 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Dnci2; Dncic2

Description (Vector)

Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. Involved in membrane-transport, such as Golgi apparatus, late endosomes and lysosomes.

Gene ID

116659

Gene Name (Vector)

dynein cytoplasmic 1 intermediate chain 2

Gene Symbol

Dync1i2

ORF Size (aa)

1899

ORF Size (bp)

1899 bp

RefSeq ID

NM_001270624

RefSeq Synonyms

NM_053880, NM_001270625, NM_001270624, BC078764,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.