rat GGT1 shRNA silencing AAV

Name
AAV-r-GGT1-shRNA

Cat No
shAAV-291948

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Rat Ggt1.

shAAV-291948

AAV-r-GGT1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Ggt1 (gamma-glutamyltransferase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

GGLUT; Ggt; Ggtp

Description (Vector)

Initiates extracellular glutathione (GSH) breakdown, provides cells with a local cysteine supply and contributes to maintain intracellular GSH level. It is part of the cell antioxidant defense mechanism. Catalyzes the transfer of the glutamyl moiety of glutathione to amino acids and dipeptide acceptors. Alternatively, glutathione can be hydrolyzed to give Cys-Gly and gamma glutamate. Isoform 3 seems to be inactive.

Gene ID

116568

Gene Name (Vector)

gamma-glutamyltransferase 1

Gene Symbol

Ggt1

ORF Size (aa)

1707

ORF Size (bp)

1707 bp

RefSeq ID

NM_053840

RefSeq Synonyms

NM_053840, BC078768,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.