rat TCFE2A shRNA silencing AAV

Name
AAV-r-TCFE2A-shRNA

Cat No
shAAV-291945

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Rat Tcf3.

shAAV-291945

AAV-r-TCFE2A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Tcf3 (transcription factor 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Pan2; Tcfe2a

Description (Vector)

Transcriptional regulator. Involved in the initiation of neuronal differentiation. Heterodimers between TCF3 and tissue-specific basic helix-loop-helix (bHLH) proteins play major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Dimers bind DNA on E-box motifs: 5'-CANNTG-3'. Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer. Binds to IEB1 and IEB2, which are short DNA sequences in the insulin gene transcription control region.

Gene ID

171046

Gene Name (Vector)

transcription factor 3

Gene Symbol

Tcf3

ORF Size (aa)

1941

ORF Size (bp)

1941 bp

RefSeq ID

NM_001035237

RefSeq Synonyms

NM_133524, NM_001035237, BC078750,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.