rat KYNU shRNA silencing AAV

Name
AAV-r-KYNU-shRNA

Cat No
shAAV-291942

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Rat Kynu.

shAAV-291942

AAV-r-KYNU-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Kynu (kynureninase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity.

Gene ID

116682

Gene Name (Vector)

kynureninase

Gene Symbol

Kynu

ORF Size (aa)

1395

ORF Size (bp)

1395 bp

RefSeq ID

NM_053902

RefSeq Synonyms

NM_053902, BC078762,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.