rat IREB2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Rat Ireb2.
shAAV-291622
AAV-r-IREB2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Rat Ireb2 (iron responsive element binding protein 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Irp2
Description (Vector)
RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.
Gene ID
64831
Gene Name (Vector)
iron responsive element binding protein 2
Gene Symbol
Ireb2
ORF Size (aa)
2892
ORF Size (bp)
2892 bp
RefSeq ID
NM_022863
RefSeq Synonyms
NM_022863, BC081798,
Species
rat
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.