rat PTBP2 shRNA silencing AAV

Cat. No: shAAV-290925

Availability: Immediate

Name: AAV-r-PTBP2-shRNA

This is an AAV expressing shRNA for silencing of Rat Ptbp2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Rat
Gene Symbol: Ptbp2
Gene Name: polypyrimidine tract binding protein 2
Gene ID: 310820
Gene Synonyms: Ptb2; PTBLP; PTBLP-L; PTBLP-S
ORF Size: 1596 bp
RefSeq#: NM_001005555
Gene Description: RNA-binding protein which binds to intronic polypyrimidine tracts and mediates negative regulation of exons splicing. May antagonize in a tissue-specific manner the ability of NOVA1 to activate exon selection. Beside its function in pre-mRNA splicing, plays also a role in the regulation of translation. Isoform 5 has a reduced affinity for RNA.