rat MCL1 shRNA silencing AAV

Name
AAV-r-MCL1-shRNA

Cat No
shAAV-290853

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Rat Mcl1.

shAAV-290853

AAV-r-MCL1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Mcl1 (BCL2 family apoptosis regulator). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.

Gene ID

60430

Gene Name (Vector)

BCL2 family apoptosis regulator

Gene Symbol

Mcl1

ORF Size (aa)

993

ORF Size (bp)

993 bp

RefSeq ID

NM_021846

RefSeq Synonyms

NM_021846, BC078835,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.