rat MAP3K11 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Rat Map3k11.
shAAV-290751
AAV-r-MAP3K11-shRNA
Ready-to-use AAV expressing shRNA for silencing of Rat Map3k11 (mitogen-activated protein kinase kinase kinase 11). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Mlk-3; Mlk3; RHOE
Description (Vector)
Activates the JUN N-terminal pathway. Required for serum-stimulated cell proliferation and for mitogen and cytokine activation of MAPK14 (p38), MAPK3 (ERK) and MAPK8 (JNK1) through phosphorylation and activation of MAP2K4/MKK4 and MAP2K7/MKK7. Plays a role in mitogen-stimulated phosphorylation and activation of BRAF, but does not phosphorylate BRAF directly. Influences microtubule organization during the cell cycle.
Gene ID
309168
Gene Name (Vector)
mitogen-activated protein kinase kinase kinase 11
Gene Symbol
Map3k11
ORF Size (aa)
2553
ORF Size (bp)
2553 bp
RefSeq ID
NM_001013150
RefSeq Synonyms
NM_001013150, BC081952,
Species
rat
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.