rat ACSL5 shRNA silencing AAV

Name
AAV-r-ACSL5-shRNA

Cat No
shAAV-290681

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Rat Acsl5.

shAAV-290681

AAV-r-ACSL5-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Acsl5 (acyl-CoA synthetase long-chain family member 5). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Acs5; Facl5

Description (Vector)

Acyl-CoA synthetases (ACSL) activate long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. ACSL5 may activate fatty acids from exogenous sources for the synthesis of triacylglycerol destined for intracellular storage (By similarity). Utilizes a wide range of saturated fatty acids with a preference for C16-C18 unsaturated fatty acids (By similarity). It was suggested that it may also stimulate fatty acid oxidation (By similarity). At the villus tip of the crypt-villus axis of the small intestine may sensitize epithelial cells to apoptosis specifically triggered by the death ligand TRAIL. May have a role in the survival of glioma cells.

Gene ID

94340

Gene Name (Vector)

acyl-CoA synthetase long-chain family member 5

Gene Symbol

Acsl5

ORF Size (aa)

2052

ORF Size (bp)

2052 bp

RefSeq ID

NM_053607

RefSeq Synonyms

NM_053607, BC072497,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.