rat RDH2 shRNA silencing AAV

Name
AAV-r-RDH2-shRNA

Cat No
shAAV-290558

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Rat Rdh16.

shAAV-290558

AAV-r-RDH2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Rdh16 (retinol dehydrogenase 16 (all-trans)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Rdh2; RoDHII

Description (Vector)

Oxidoreductase with a preference for NAD. Oxidizes all-trans-retinol and 13-cis-retinol to the corresponding aldehydes. Has higher activity towards CRBP-bound retinol than with free retinol. Oxidizes 3-alpha-hydroxysteroids. Oxidizes androstanediol and androsterone to dihydrotestosterone and androstanedione. Can also catalyze the reverse reaction.

Gene ID

299511

Gene Name (Vector)

retinol dehydrogenase 16 (all-trans)

Gene Symbol

Rdh16

ORF Size (aa)

954

ORF Size (bp)

954 bp

RefSeq ID

NM_199208

RefSeq Synonyms

NM_199208, BC079153, BC062000,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.