rat DAB2IP shRNA silencing AAV

Name
AAV-r-DAB2IP-shRNA

Cat No
shAAV-290504

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Rat Dab2ip.

shAAV-290504

AAV-r-DAB2IP-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Dab2ip (DAB2 interacting protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

DIP1/2

Description (Vector)

Functions as a Ras GTPase-activating protein (By similarity). Through its interaction with MAP3K5 disrupts the association of MAP3K5 with the inhibitory 14-3-3 complex. Mediates TNF/TRAF2-induced MAP3K5-JNK activation, while it inhibits CHUK-NF-kappa-B signaling. May act as a tumor suppressor gene.

Gene ID

192126

Gene Name (Vector)

DAB2 interacting protein

Gene Symbol

Dab2ip

ORF Size (aa)

2991

ORF Size (bp)

2991 bp

RefSeq ID

NM_138710

RefSeq Synonyms

NM_138710, BC061865,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.