rat ZDHHC7 shRNA silencing AAV

Name
AAV-r-ZDHHC7-shRNA

Cat No
shAAV-290362

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Rat Zdhhc7.

shAAV-290362

AAV-r-ZDHHC7-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Zdhhc7 (zinc finger, DHHC-type containing 7). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

DHHC7; Serz-1; Serz1

Description (Vector)

Palmitoyltransferase with broad specificity. Palmitoylates SNAP25 and DLG4/PSD95. May palmitoylate GABA receptors on their gamma subunit (GABRG1, GABRG2 and GABRG3) and thereby regulate their synaptic clustering and/or cell surface stability (By similarity). Palmitoylates sex steroid hormone receptors, including ESR1, PGR and AR, thereby regulating their targeting to the plasma membrane. This affects rapid intracellular signaling by sex hormones via ERK and AKT kinases and the generation of cAMP, but does not affect that mediated by their nuclear receptors.

Gene ID

170906

Gene Name (Vector)

zinc finger, DHHC-type containing 7

Gene Symbol

Zdhhc7

ORF Size (aa)

927

ORF Size (bp)

927 bp

RefSeq ID

NM_133394

RefSeq Synonyms

NM_133394, BC061769,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.