rat PRDX1 shRNA silencing AAV

Name
AAV-r-PRDX1-shRNA

Cat No
shAAV-290203

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Rat Prdx1.

shAAV-290203

AAV-r-PRDX1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Prdx1 (peroxiredoxin 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Hbp23

Description (Vector)

Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation (By similarity).

Gene ID

117254

Gene Name (Vector)

peroxiredoxin 1

Gene Symbol

Prdx1

ORF Size (aa)

600

RefSeq ID

NM_057114

RefSeq Synonyms

NM_057114, BC088118, BC058450,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.