rat MIF shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Rat Mif.
shAAV-290111
AAV-r-MIF-shRNA
Ready-to-use AAV expressing shRNA for silencing of Rat Mif (macrophage migration inhibitory factor (glycosylation-inhibiting factor)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity.
Gene ID
81683
Gene Name (Vector)
macrophage migration inhibitory factor (glycosylation-inhibiting factor)
Gene Symbol
Mif
ORF Size (aa)
348
RefSeq ID
NM_031051
RefSeq Synonyms
NM_031051, BC061545,
Species
rat
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.