mouse TICAM2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Ticam2.
shAAV-281160
AAV-m-TICAM2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Ticam2 (toll-like receptor adaptor molecule 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
B430113A10; TICAM-2; Tirp; TRAM; Trif
Description (Vector)
Functions in LPS-TLR4 signaling to regulate the MYD88-independent pathway during the innate immune response to LPS. Also involved in IL1-triggered NF-kappa-B activation, functioning upstream of IRAK1, IRAK2, TRAF6, and IKBKB. Physically bridges TLR4 and TICAM1 and functionally transmits LPS-TRL4 signal to TICAM1.
Gene ID
225471
Gene Name (Vector)
toll-like receptor adaptor molecule 2
Gene Symbol
Ticam2
ORF Size (aa)
699
ORF Size (bp)
699 bp
RefSeq ID
NM_173394
RefSeq Synonyms
NM_173394, BC099933,
Species
mouse
UniGene ID
Mm.149280
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.