mouse SNCAIP shRNA silencing AAV

Name 
AAV-m-SNCAIP-shRNA
Cat No 
shAAV-281120
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Sncaip.

shAAV-281120
AAV-m-SNCAIP-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Sncaip (synuclein, alpha interacting protein (synphilin)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
88
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2810407O15Rik; 4933427B05Rik; BB104594; SYPH1
Description (Vector)
Isoform 2 inhibits the ubiquitin ligase activity of SIAH1 and inhibits proteasomal degradation of target proteins. Isoform 2 inhibits autoubiquitination and proteasomal degradation of SIAH1, and thereby increases cellular levels of SIAH. Isoform 2 modulates SNCA monoubiquitination by SIAH1.
Gene ID
67847
Gene Name (Vector)
synuclein, alpha interacting protein (synphilin)
Gene Symbol
Sncaip
ORF Size (aa)
2898
ORF Size (bp)
2898 bp
RefSeq ID
NM_026408
RefSeq Synonyms
NM_026408, NM_001199154, NM_001199153, NM_001199151, BC098489,
Species
mouse
UniGene ID
Mm.292168

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.